Rear Admiral Declan Ford arrives at Starbase 104 and finds the Artemis in dock and without a crew. He quickly assembles the best of the best in their fields. This starts with the command team of Captain Marc Kidd and XO Kayleigh Harper. The trio must act quickly and assemble the rest of the crew, for every moment they are in dock, is another moment that attacks on the Federation are executed.
The Artemis' crew comes aboard and gets to know each other in this the Pilot episode of SCIU: Artemis.
While en route to Andorra with the Federation President, Starfleet Commander Ray Trapp dies of an apparent stroke after having lunch with the President. Despite the efforts of the President's personal medical team the Commander dies. The Artemis intercepts the President's ship half way to Andorra. Trapp was tasked with keeping the defense codes to Earth's planetary defense systems. He was to stay at the President's side during the trip. The crew of the Artemis must investigate this mysterious death with an apparent link to an assassination attempt on the President, all before the assassin strikes again.